Epistemology is the basic subject of every science that is discourse the nature of science and the manner to recgnize of
it. Edistemology make investigation of knowledge a science and study the value of every science.
In epistemology pay attention to know kinde os human acquaintance, and the origins of it, and investigate the measure and criterion of each knowledge.
In this paper tried to define epistemoloty, investigate of different historical during of it, analysis of it in organization and management science, introduce foundation of organizational epistemology and knowledge basics of some organization and managerial science theorists.